Neurology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Figures Only
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Data Supplement
Right arrow Spanish Translation
Right arrow Correspondence:
Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when Correspondence are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Sveen, M. -L.
Right arrow Articles by Vissing, J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Sveen, M. -L.
Right arrow Articles by Vissing, J.
Related Collections
Right arrow Muscle disease
Right arrow All Clinical trials
Right arrow Clinical trials Observational study (Cohort, Case control)
Right arrowRelated Article
NEUROLOGY 2007;68:59-61
© 2007 American Academy of Neurology

Endurance training

An effective and safe treatment for patients with LGMD2I

M. -L. Sveen, MD, T. D. Jeppesen, MD, S. Hauerslev, BSc, T. O. Krag, PhD and J. Vissing, MD, PhD

From the Neuromuscular Research Unit, Department of Neurology and the Copenhagen Muscle Research Center, National University Hospital, Rigshospitalet, Copenhagen, Denmark.

Address correspondence and reprint requests to Dr. Marie-Louise Sveen, Department of Neurology 2082, Rigshospitalet, Blegdamsvej 9, DK-2100 Copenhagen, Denmark; e-mail: RH18329{at}rh.hosp.dk

We studied the effect of aerobic training on conditioning in patients with limb-girdle muscular dystrophy type 2I (LGMD2I). Nine patients with LGMD2I cycled fifty 30-minute sessions at 65% of their maximal oxygen uptake over 12 weeks. Training significantly improved work capacity, paralleled by self-reported improvements. Creatine kinase levels did not increase significantly, and muscle morphology was unaffected. Moderate-intensity endurance training is a safe method to increase exercise performance and daily function in patients with LGMD2I.

Additional material related to this article can be found on the Neurology Web site. Go to www.neurology.org and scroll down the Table of Contents for the January 2 issue to find the title link for this article.

This project was supported by grants from the Danish Medical Research Council (nos. 22-00-1056 and 22-03-0474), the Novo Nordisk Foundation, the University of Copenhagen, the Copenhagen Hospital Corporation (H:S).

Disclosure: The authors report no conflicts of interest.

Received May 1, 2006. Accepted in final form September 20, 2006.


Related Article

January 2 Highlights
Neurology 2007 68: 4-5. [Full Text] [PDF]



This article has been cited by other articles:


Home page
 BrainHome page
M. L. Sveen, T. D. Jeppesen, S. Hauerslev, L. Kober, T. O. Krag, and J. Vissing
Endurance training improves fitness and strength in patients with Becker muscular dystrophy
Brain, November 1, 2008; 131(11): 2824 - 2831.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2007 by AAN Enterprises, Inc.