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NEUROLOGY 2006;67:1303-1304
© 2006 American Academy of Neurology
Brief Communications

Metastases to the pineal gland

Andrew B. Lassman, MD, Jeffrey N. Bruce, MD and Michael R. Fetell, MD

From the Department of Neurology (A.B.L.), Memorial Sloan-Kettering Cancer Center, New York, NY; Department of Neurological Surgery (J.N.B.), New York-Presbyterian Hospital, Columbia University Medical Center, New York, NY; and Ivax Research (M.R.F.), Miami, FL

Address correspondence and reprint requests to Dr. Andrew B. Lassman, Department of Neurology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021; e-mail: lassmana{at}mskcc.org

We identified 10 patients with symptomatic metastases to the pineal gland. We present the clinical and radiographic findings in this syndrome. Leptomeningeal metastases occur frequently and are a poor prognostic factor. In all cases, the primary cancer was clinically silent, either in remission (six cases) or previously undiagnosed (four cases). Hence, metastatic disease, albeit uncommon, should be considered in the differential diagnosis of pineal tumors.

Additional material related to this article can be found on the Neurology Web site. Go to www.neurology.org and scroll down the Table of Contents for the October 10 issue to find the title link for this article.

Supported in part by the American Brain Tumor Association.

Disclosure: The authors report no conflicts of interest.

Received January 5, 2006. Accepted in final form June 16, 2006.






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