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NEUROLOGY 2006;66:239-242
© 2006 American Academy of Neurology
Brief Communications

Surviving glioblastoma for more than 5 years: The patient's perspective

J. P. Steinbach, MD, H. -P. Blaicher, PhD, U. Herrlinger, MD, W. Wick, MD, T. Nägele, MD, R. Meyermann, MD, M. Tatagiba, MD, M. Bamberg, MD, J. Dichgans, MD, H. -O. Karnath, MD, PhD and M. Weller, MD

From the Departments of General (J.P.S., U.H., W.W., J.D., M.W.) and Cognitive Neurology (H.-P.B., H.-O.K.), Hertie Institute for Clinical Brain Research, and Departments of Neuroradiology (T.N.), Neuropathology (R.M.), Neurosurgery (M.T.), and Radiation Oncology (M.B.), University of Tübingen, School of Medicine, Tübingen, Germany.

Address correspondence and reprint requests to Dr. Joachim P. Steinbach, Department of General Neurology, University of Tübingen, Medical School, Hoppe-Seyler-Strasse 3, 72076 Tübingen, Germany; e-mail: joachim.steinbach{at}uni-tuebingen.de.

The authors performed a comprehensive analysis of the functional outcome of 10 patients who had survived 5 years from a diagnosis of glioblastoma. Neurologic deficits were mild in most patients, but neuropsychological testing demonstrated cognitive deficits in all patients. Depression and anxiety were common. Although most patients thought that their social functioning and work ability were impaired, little reduction in overall quality of life was perceived.

Additional material related to this article can be found on the Neurology Web site. Go to www.neurology.org and scroll down the Table of Contents for the January 24 issue to find the title link for this article.

Supported by the Jaqueline Seroussi Memorial Foundation.

Disclosure: The authors report no conflicts of interest.

Received May 20, 2005. Accepted in final form October 7, 2005.




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