Neurology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Figures Only
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Data Supplement
Right arrow Correspondence:
Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when Correspondence are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Badjatia, N.
Right arrow Articles by Rordorf, G. A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Badjatia, N.
Right arrow Articles by Rordorf, G. A.
Related Collections
Right arrow All Clinical trials
Right arrow All Cerebrovascular disease/Stroke
Right arrow Clinical trials Observational study (Cohort, Case control)
Right arrow Brain trauma
Right arrow Arteriovenous malformation
Right arrow Infarction
Right arrowRelated Article
NEUROLOGY 2006;66:1739-1741
© 2006 American Academy of Neurology
Brief Communications

Rapid infusion of cold saline (4 °C) as adjunctive treatment of fever in patients with brain injury

Neeraj Badjatia, MD, Michael Bodock, PharmD, M. Guanci, CNRN and G. A. Rordorf, MD

From the Departments of Neurology (N.B., M.G., G.A.R.) and Pharmacy (M.B.), Massachusetts General Hospital, Harvard Medical School, Boston, MA.

Address correspondence and reprint requests to Dr. Neeraj Badjatia, Division of Stroke and Critical Care, Columbia University College of Physicians and Surgeons, Neurological Institute, 710 West 168th Street, Box 29, New York NY 10032; e-mail: nbadjatia{at}neuro.columbia.edu

The use of rapid infusion of large-volume cold saline (CS) as an adjunctive therapy for treating refractory fever in nine patients is reported. A decline in temperature (39.2 ± 0.3 vs 37.1 ± 1.2 °C, p = 0.006) at 2 hours and fever burden (97.3 ± 343.8 vs 734.3 ± 422.3 °C*min, p = 0.02) at 12 hours was noted after CS bolus. Rapid infusion of large-volume CS may be used as an adjunct for inducing normothermia in refractory febrile patients.

Additional material related to this article can be found on the Neurology Web site. Go to www.neurology.org and scroll down the Table of Contents for the June 13 issue to find the title link for this article.

Disclosure: The authors report no conflicts of interest.

Received November 11, 2005. Accepted in final form February 22, 2006.


Related Article

June 13 Highlights
Neurology 2006 66: 1616-1617. [Full Text] [PDF]



This article has been cited by other articles:


Home page
 J. Appl. Physiol.Home page
M. A. Neimark, A.-A. Konstas, A. F. Laine, and J. Pile-Spellman
Integration of jugular venous return and circle of Willis in a theoretical human model of selective brain cooling
J Appl Physiol, November 1, 2007; 103(5): 1837 - 1847.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2006 by AAN Enterprises, Inc.