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Pick’s disease: A clinical overview

From the Dementia Research Group, The National Hospital for Neurology and Neurosurgery, Queen Square, London, UK.

Address correspondence and reprint requests to Professor Martin N. Rossor, Dementia Research Group, The National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, United Kingdom; e-mail: mrossor{at}dementia.ion.ucl.ac.uk

What is to be understood by the term Pick’s disease? Is this a clinical syndrome(s) of frontotemporal lobar atrophy, or a more specific clinicopathological concept of frontotemporal lobar atrophy with Pick bodies and/or Pick cells on neuropathology? The author discusses these concepts in an historical context as an introduction to this symposium.

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