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Volume 56, Number 12, June 26, 2001
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Neurology 2001;56:1637-1643
© 2001 American Academy of Neurology


Articles

Handicap after acute whiplash injury

A 1-year prospective study of risk factors

Helge Kasch, MD, PhD;, Flemming W. Bach, MD, PhD; and Troels S. Jensen, MD, PhD

From the Department of Neurology, Aarhus University Hospital, and Danish Pain Research Centre, Aarhus University, Denmark.

Address correspondence and reprint requests to Dr. Helge Kasch, Danish Pain Research Centre, Aarhus University Hospital, Noerrebrogade 44, Building 1C, DK-8000 Aarhus C, Denmark; e-mail: helge{at}akhphd.au.dk

BACKGROUND: Exposure to a whiplash injury implies a risk for development of chronic disability and handicap, with reported frequencies ranging from 0% to 50% in follow-up studies. The exact risk for development of chronic whiplash syndrome is not known.

OBJECTIVE: To prospectively determine the sensitivity and specificity of five possible predictors for handicap following a whiplash injury.

METHODS: In a 1-year prospective study of persons with acute whiplash injury (n = 141) and control subjects who had acute ankle distortion (n = 40), pain intensity, number of nonpainful neurologic complaints, cervical mobility, workload during extension and flexion of the neck, and results of psychometric assessment were recorded. The consecutively sampled injured persons were assessed with structured and semistructured questionnaires, and underwent neurologic examination after 1 week and 1, 3, 6, and 12 months. After 3 to 4 years, participants with whiplash injury were questioned about legal issues.

RESULTS: After 1 year, 11 (7.8%) persons with whiplash injury had not returned to usual level of activity or work. The best single estimator of handicap was the cervical range-of-motion test, which had a sensitivity of 73% and a specificity of 91% (p < 0.01, Cox regression analysis). Accuracy and specificity increased to 94% and 99% when combined with pain intensity and other complaints. This increase was gained at the expense of a reduced sensitivity. Initiation of lawsuit within first month after injury did not influence recovery.

CONCLUSION: The cervical range-of-motion test has a high sensitivity in prediction of handicap after acute whiplash injury. The value of cervical range-of-motion test is further improved by additional recording of symptoms and pain intensity.




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Correspondence:

Read all Correspondence

Handicap after acute whiplash injury: A 1-year prospective study of risk factors
Michael I Weintraub
Neurology Online, 19 Sep 2001 [Full text]
Handicap after acute whiplash injury: A 1-year prospective study of risk factors
Steven Mandel
Neurology Online, 19 Sep 2001 [Full text]
Reply to letters from Michael I Weintraub and Steven Mandel
H Kasch, et al.
Neurology Online, 19 Sep 2001 [Full text]
Re: Handicap after acute whiplash injury: A 1-year prospective study of risk factors
Roland W Schelter
Neurology Online, 10 Dec 2001 [Full text]
Reply to Schelter
H. Kasch, et al.
Neurology Online, 22 Dec 2001 [Full text]



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