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The effect of flunarizine on essential tremor

Department of Clinical Neurosciences (Drs. Biary and Al Deeb), Riyadh Armed Forces Hospital, Riyadh, Kingdom of Saudi Arabia, and Epidemiology/Biostatistics (Dr. Langenberg), School of Public Health, University of Illinois, Chicago.

We investigated the effect of flunarizine treatment (10 mg/d) in 17 subjects with essential tremor in a double-blind placebo-controlled design. Tremor was assessed by clinical scoring, tremographic recordings, and subjective rating by subjects. Of the 15 subjects who completed the study, 13 showed improvement. We conclude that flunarizine is effective treatment for essential tremor.

Address correspondence and reprint requests to Dr. Nabil Biary, Department of Clinical Neurosciences, Riyadh Armed Forces Hospital, PO Box 7897, Riyadh 11159, Kingdom of Saudi Arabia.

Received April 28, 1990. Accepted for publication in final form July 16,1990.