Neurology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Correspondence:
Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when Correspondence are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Reed, B. R.
Right arrow Articles by Ober, B. A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Reed, B. R.
Right arrow Articles by Ober, B. A.
NEUROLOGY 1989;39:1537
© 1989 American Academy of Neurology

Memory and regional cerebral blood flow in mildly symptomatic Alzheimer's disease

Bruce R. Reed, PhD, William J. Jagust, MD, J. Philip Seab, MD and Beth A. Ober, PhD

From the Department of Neurology (Drs. Reed, Jagust, and Seab), School of Medicine, University of California, Davis, and Veterans Administration Medical Center, Martinez, CA; Donner Laboratory (Drs. Jagust and Seab), Lawrence Berkeley Laboratory, University of California, Berkeley, CA; and Veterans Administration Medical Center (Dr. Ober), Livermore, CA.

We performed SPECT perfusion imaging and memory testing with mildly and moderately demented Alzheimer's disease (AD) patients and with healthy controls. All patients had memory abnormalities, but 5 of the 21 patients had neither temporal nor parietal perfusion abnormalities, indicating that temporoparietal blood flow may be normal at a point when memory is pathologic and the clinical diagnosis of AD is possible.

Address correspondence and reprint requests to Dr. Reed, University of California, Davis, Northern California Alzheimer's Disease Center, Herrick Hospital and Health Center, 2001 Dwight Way, Berkeley, CA 94704.

Supported by NIH grants AG05890 and AG07793 from the National Institute on Aging.

Received December 30, 1988. Accepted for publication in final form May 23, 1989.




This article has been cited by other articles:


Home page
 NeurologyHome page
L. Mosconi, W. -H. Tsui, S. De Santi, J. Li, H. Rusinek, A. Convit, Y. Li, M. Boppana, and M. J. de Leon
Reduced hippocampal metabolism in MCI and AD: Automated FDG-PET image analysis
Neurology, June 14, 2005; 64(11): 1860 - 1867.
[Abstract] [Full Text] [PDF]

Home page
 ANN INTERN MEDHome page
C. M. Clark and J. H.T. Karlawish
Alzheimer Disease: Current Concepts and Emerging Diagnostic and Therapeutic Strategies
Ann Intern Med, March 4, 2003; 138(5): 400 - 410.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Neuroradiol.Home page
A. Bozzao, R. Floris, M. E. Baviera, A. Apruzzese, and G. Simonetti
Diffusion and Perfusion MR Imaging in Cases of Alzheimer's Disease: Correlations with Cortical Atrophy and Lesion Load
AJNR Am. J. Neuroradiol., June 1, 2001; 22(6): 1030 - 1036.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
R. J. Perry and J. R. Hodges
Attention and executive deficits in Alzheimer's disease: A critical review
Brain, March 1, 1999; 122(3): 383 - 404.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1989 by AAN Enterprises, Inc.