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NEUROLOGY 1989;39:1509
© 1989 American Academy of Neurology

Progression of hypertensive intracerebral hemorrhage

S. T. Chen, MD, S. D. Chen, MD, C. Y. Hsu, MD, PhD and E. L. Hogan, MD

From the Department of Neurology, Chang Gung Memorial Hospital (CGMH), Taipei, Taiwan.

Hypertensive intracerebral hemorrhage (HICH) is generally considered to be a monophasic event. Enlargement of the initial hematoma after several hours or days has rarely been documented. We describe the clinical and CT findings in 8 patients (5 men, 3 women, aged 39 to 68 years) with continued bleeding or rebleeding during the acute phase of HICH. The thalamus was the most frequent site of hemorrhage (6/8). The neurologic status deteriorated in all: 6 within 24 hours, and 2 after 5 and 7 days. Persistent hypertension was common (6/8) prior to extension of the hemorrhage. The 2nd CT revealed an obvious increase in hematoma size in all cases. Four patients died and 4 survived with severe neurologic disability. These serial studies indicate that active bleeding or rebleeding can occur in HICH and suggests that the risk is particularly high with thalamic hemorrhage. We conclude that meticulous control of hypertension after HICH may be justified in selected patients.

Address correspondence and reprint requests to Dr. S. T. Chen, Department of Neurology, Chang Gung Memorial Hospital, 199 Tung Hwa North Road, Taipei, Taiwan.

Received February 14, 1989. Accepted for publication in final form May 17, 1989.




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