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NEUROLOGY 1987;37:276
© 1987 American Academy of Neurology

Recognizing neurotoxic disease

H. H. Schaumburg, MD and P. S. Spencer, PhD, MRC Path

Departments of Neurology, Neuroscience, and Pathology (Neuropathology) and the Institute of Neurotoxicology, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, NY.

We review issues that cloud the diagnosis of neurotoxic disease, and stress the importance of a directed history. Since an enormous number of potentially toxic chemicals are now deployed in the environment, workplace, and pharmaceuticals, it is essential that physicians be alert to elementary principles of clinical neurotoxicology in order that they pinpoint genuine instances of neurotoxicity and not alarm the public with spurious cases.

Address correspondence and reprint requests to Dr. Schaumburg, Department of Neurology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461.

Received April 17, 1986. Accepted fix publication May 14, 1986.

Supported in part by USPHS grants OH 00851, OH 99535, and NS 19611.




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