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Probing for the human coronavirus OC43 in multiple sclerosis

Cytobiology Group, Department of Microbiology and Immunology (Drs. Sorensen, Flintoff, and Dales), University of Western Ontario, London, Ontario, Canada; the Department of Microbiology (Dr. Collins), State University of New York at Buffalo, Buffalo, NY; and the Department of Clinical Neurological Science (Dr. Ebers), University Hospital, University of Western Ontario, London, Ontario, Canada.

Tissues acquired at autopsy from four patients with MS and biopsies from one patient with a probable diagnosis of MS were probed for the presence of OC43 RNA. This human coronavirus was not detected.

Address correspondence and reprint requests to Dr. Dales, Department of Microbiology and Immunology, University of Western Ontario, London, Ontario, Canada N6A 5C1.

Supported by the Multiple Sclerosis Society of Canada and by the Medical Research Council of Canada.

Accepted for publication March 26, 1986.

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