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Phenobarbital-induced dyskinesia in a neurologically impaired child

From the Division of Neurology, The Children's Hospital of Philadelphia and the Departments of Neurology and Pediatrics, University of Pennsylvania School of Medicine, Philadelphia.

A 2-year-old child with known neurologic impairment developed a dyskinesia soon after starting phenobarbital therapy for seizures. Known causes of movement disorders were eliminated after evaluation. On repeat challenge with phenobarbital, the dyskinesia recurred. Phenobarbital should be added to the list of anticonvulsant drugs that can cause movement disorders.

Address correspondence and reprint requests to Dr. Younkin, Division of Neurology, The Children's Hospital of Philadelphia, 34th Street & Civic Center Boulevard, Philadelphia, PA 19104.

Dr. Younkin is the recipient of Teacher-Investigator Award NS 00774-01 from the National Institute of Neurologic and Communicative Disorders and Stroke.

Accepted for publication March 22, 1984.

This article has been cited by other articles:

				C Zadikoff, R P Munhoz, A N Asante, N Politzer, R Wennberg, P Carlen, and A Lang Movement disorders in patients taking anticonvulsants J. Neurol. Neurosurg. Psychiatry, February 1, 2007; 78(2): 147 - 151. [Abstract] [Full Text] [PDF]