|
|
||||||||
From the Department of Medicine, Divisions of Cardiology and Neurology, Duke University Medical Center, Durham, NC.
We used a computer data bank to evaluate 740 consecutive patients admitted to a cardiac care unit with myocardial infarction. Stroke occurred in 18 (2.4%) patients in the hospital; the anterior circulation was involved in 76% of strokes. Hospital mortality was 61% in patients with stroke and 13% in patients without stroke. Atrial arrhythmia was a significant (p 5 0.03) risk factor for stroke, but peak creatine kinase and ventricular arrhythmia were not. Cardiac pump failure, apical or anterior-lateral myocardial infarction, and history of previous stroke were associated with an increased risk of stroke. Clinical and pathologic data suggested an embolic etiology for most strokes that complicate acute myocardial infarction.
Address correspondence and reprint requests to Dr. Coffey, Box 3903, Duke Medical Center, Durham, NC 27710.
Supported by Contract HRA 230-76-0300 and Research Grants HS-03834 and HS-048473 from the National Center for Health Services Research-OASH; Research Grant HL-17670 from the National Heart, Lung and Blood Institute; Training Grant LM-07003 and Grants LM-03373 and LM-00042 from the National Library of Medicine; and Grants from the Prudential Insurance Company of America, the Kaiser Family Foundation, and the Andrew W. Mellon Foundation.
Presented in part at the thirty-fifth annual meeting of the American Academy of Neurology, San Diego, CA, April 28, 1983.
Accepted for publication March 8, 1984.
This article has been cited by other articles:
![]() |
E. Van De Graaff, M. Dutta, P. Das, E. A. Shry, P. D. Frederick, M. Blaney, D. J. Pasta, and S. R. Steinhubl Early Coronary Revascularization Diminishes the Risk of Ischemic Stroke With Acute Myocardial Infarction Stroke, October 1, 2006; 37(10): 2546 - 2551. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. I. Suarez Acute Myocardial Infarction, Ischemic Stroke, Sympathetic Stress, and Inflammation: Birds of a Feather Stroke, October 1, 2006; 37(10): 2449 - 2450. [Full Text] [PDF] |
||||
![]() |
L. B. Goldstein, R. Adams, M. J. Alberts, L. J. Appel, L. M. Brass, C. D. Bushnell, A. Culebras, T. J. DeGraba, P. B. Gorelick, J. R. Guyton, et al. Primary Prevention of Ischemic Stroke: A Guideline From the American Heart Association/American Stroke Association Stroke Council: Cosponsored by the Atherosclerotic Peripheral Vascular Disease Interdisciplinary Working Group; Cardiovascular Nursing Council; Clinical Cardiology Council; Nutrition, Physical Activity, and Metabolism Council; and the Quality of Care and Outcomes Research Interdisciplinary Working Group: The American Academy of Neurology affirms the value of this guideline. Circulation, June 20, 2006; 113(24): e873 - e923. [Abstract] [Full Text] [PDF] |
||||
![]() |
L. B. Goldstein, R. Adams, M. J. Alberts, L. J. Appel, L. M. Brass, C. D. Bushnell, A. Culebras, T. J. DeGraba, P. B. Gorelick, J. R. Guyton, et al. Primary Prevention of Ischemic Stroke: A Guideline From the American Heart Association/American Stroke Association Stroke Council: Cosponsored by the Atherosclerotic Peripheral Vascular Disease Interdisciplinary Working Group; Cardiovascular Nursing Council; Clinical Cardiology Council; Nutrition, Physical Activity, and Metabolism Council; and the Quality of Care and Outcomes Research Interdisciplinary Working Group: The American Academy of Neurology affirms the value of this guideline. Stroke, June 1, 2006; 37(6): 1583 - 1633. [Abstract] [Full Text] [PDF] |
||||
![]() |
L. B. Goldstein, R. Adams, K. Becker, C. D. Furberg, P. B. Gorelick, G. Hademenos, M. Hill, G. Howard, V. J. Howard, B. Jacobs, et al. Primary Prevention of Ischemic Stroke : A Statement for Healthcare Professionals From the Stroke Council of the American Heart Association Circulation, January 2, 2001; 103(1): 163 - 182. [Full Text] [PDF] |
||||
![]() |
L. B. Goldstein, R. Adams, K. Becker, C. D. Furberg, P. B. Gorelick, G. Hademenos, M. Hill, G. Howard, V. J. Howard, B. Jacobs, et al. Primary Prevention of Ischemic Stroke : A Statement for Healthcare Professionals From the Stroke Council of the American Heart Association Stroke, January 1, 2001; 32(1): 280 - 299. [Full Text] [PDF] |
||||
![]() |
Z. G. Nadareishvili, Z. Choudary, C. Joyner, D. Brodie, and J. W. Norris Cerebral Microembolism in Acute Myocardial Infarction Stroke, December 1, 1999; 30(12): 2679 - 2682. [Abstract] [Full Text] [PDF] |
||||
![]() |
K. W. Mahaffey, R. A. Harrington, M. L. Simoons, C. B. Granger, C. Graffagnino, M. J. Alberts, D. T. Laskowitz, J. M. Miller, M. A. Sloan, L. G. Berdan, et al. Stroke in Patients With Acute Coronary Syndromes : Incidence and Outcomes in the Platelet Glycoprotein IIb/IIIa in Unstable Angina: Receptor Suppression Using Integrilin Therapy (PURSUIT) Trial Circulation, May 11, 1999; 99(18): 2371 - 2377. [Abstract] [Full Text] [PDF] |
||||
![]() |
D. Tanne, S. Gottlieb, A. Caspi, H. Hod, A. Palant, L. Reisin, T. Rosenfeld, B. Peled, A. T. Marmor, J. Balkin, et al. Treatment and Outcome of Patients With Acute Myocardial Infarction and Prior Cerebrovascular Events in the Thrombolytic Era: The Israeli Thrombolytic National Survey Arch Intern Med, March 23, 1998; 158(6): 601 - 606. [Abstract] [Full Text] [PDF] |
||||
![]() |
K. W. Mahaffey, C. B. Granger, M. A. Sloan, T. D. Thompson, J. M. Gore, W. D. Weaver, H. D. White, M. L. Simoons, G. I. Barbash, E. J. Topol, et al. Risk Factors for In-hospital Nonhemorrhagic Stroke in Patients With Acute Myocardial Infarction Treated With Thrombolysis : Results From GUSTO-I Circulation, March 3, 1998; 97(8): 757 - 764. [Abstract] [Full Text] [PDF] |
||||
![]() |
K. C. Wu, E. A. Zerhouni, R. M. Judd, C. H. Lugo-Olivieri, L. A. Barouch, S. P. Schulman, R. S. Blumenthal, and J. A. C. Lima Prognostic Significance of Microvascular Obstruction by Magnetic Resonance Imaging in Patients With Acute Myocardial Infarction Circulation, March 3, 1998; 97(8): 765 - 772. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. A. Sloan, T. R. Price, M. L. Terrin, S. Forman, J. M. Gore, B. R. Chaitman, M. Hodges, H. Mueller, W. J. Rogers, G. L. Knatterud, et al. Ischemic Cerebral Infarction After rt-PA and Heparin Therapy for Acute Myocardial Infarction : The TIMI-II Pilot and Randomized Clinical Trial Combined Experience Stroke, June 1, 1997; 28(6): 1107 - 1114. [Abstract] [Full Text] |
||||
![]() |
T. Mooe, P. Eriksson, and B. Stegmayr Ischemic Stroke After Acute Myocardial Infarction : A Population-Based Study Stroke, April 1, 1997; 28(4): 762 - 767. [Abstract] [Full Text] |
||||
![]() |
E. Loh, M. St. J. Sutton, C.-C. C. Wun, J. L. Rouleau, G. C. Flaker, S. S. Gottlieb, G. A. Lamas, L. A. Moye, S. Z. Goldhaber, and M. A. Pfeffer Ventricular Dysfunction and the Risk of Stroke after Myocardial Infarction N. Engl. J. Med., January 23, 1997; 336(4): 251 - 257. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. Nishino, K. Sueyoshi, M. Yasuno, Y. Yamada, H. Abe, M. Hori, and T. Kamada Risk Factors for Carotid Atherosclerosis and Silent Cerebral Infarction in Patients with Coronary Heart Disease Angiology, June 1, 1993; 44(6): 432 - 440. [Abstract] [PDF] |
||||
![]() |
A. Ramani, U. Shetty, and G.N. Kundaje Electrocardiographic Abnormalities in Cerebrovascular Accidents Angiology, September 1, 1990; 41(9): 681 - 686. [Abstract] [PDF] |
||||
![]() |
J. Hirsh and J. A. Cairns Analytic Reviews : Antithrombotic Tberapy in Acute Myocardial Infarction and Unstable Angina J Intensive Care Med, November 1, 1987; 2(6): 299 - 312. [PDF] |
||||
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |