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From the Stroke Service and Departments of Neurology (Drs. Gorelick, Caplan, and Hier, and Ms Parker) and Diagnostic Radiology (Neuroradiology Section)(Dr Patel), Michael Reese Hospital and Medical Center, Chicago, IL
We compared clinical and angiographic features of 26 white and 45 black patients with symptomatic occlusive cerebrovascular disease. White patients had more transient ischemic attacks, carotid bruits, and more severe occlusive disease of the internal carotid artery origin. Blacks had more severe disease of the middle cerebral artery stem and supraclinoid internal carotid arteries. Differences were not explained by racial differences in the prevalence of hypertension, diabetes, hypercholesterolemia, or ischemic heart disease. Since the middle cerebral artery lesions in blacks do not correlate with other accepted epidemiologic, clinical, and laboratory markers of atherosclerosis, the lesions may arise from a disorder that differs from atherosclerosis.
Address correspondence and reprint requests to Dr Caplan, Department of Neurology, Michael Reese Hospital and Medical Center, 29th and Ellis Avenue, Chicago, IL 60616.
Supported in part by the AMOCO Foundation
Accepted for publication April 18, 1983.
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