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Nonhemorrhagic infarction of the thalamus

Behavioral, anatomic, and physiologic correlates

From the Department of Neurology (Division of Behavioral Neurology), University of Iowa College of Medicine, Iowa City, IA.

We studied five patients with nonhemorrhagic thalamic infarction with neuropsychological tests, CT, and somatosensory evoked responses (SERs). The three patients with left thalamic lesions had abnormalities of language, memory, visuospatial processing, intellect, and personality—changes compatible with dementia. The two patients with right thalamic lesions were not aphasic and did not have verbal memory defects, but were otherwise comparable. Four lesions occurred in the tuberothalamic artery territory and one in the deep interpeduncular artery territory. SERs revealed a delay in the first negative peak after P₁₄ in the tuberothalamic patients, and a delay in the third negative peak (N₆₀ in all patients.

Address correspondence and reprint requests to Dr. Graff-Ffadford, Department of Neurology, University of Iowa Hospitals and Clinics, Iowa City, IA 52242.

Accepted for publication April 13, 1983.

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