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NEUROLOGY 1983;33:1233
© 1983 American Academy of Neurology

Blink-saccade synkinesis

David S. Zee, Fred C. Chu, R. John Leigh, Peter J. Savino, Norman J. Schatz, Douglas B. Reingold and David G. Cogan

Neuro-Ophthalmology Section, Clinical Branch, National Eye Institute, Bethesda, MD; Department of Neurology and Ophthalmology, Johns Hopkins Hospital, Baltimore, MD; and Neuro-Ophthalmology Unit, Wills Eye Hospital, Philadelphia, PA.

We studied two patients who could make saccades of normal velocity and amplitude only in association with a simultaneous blink. In one patient, the initiation of saccades was also facilitated by blinks. Both patients had signs of cerebellar or brainstem dysfunction, suggesting a posterior fossa localization for blink facilitation of saccadic velocity and amplitude.

Address correspondence and reprint requests to Dr. Zee, Department of Neurology, Meyer-2–136, The Johns Hopkins Hospital, Baltimore, MD 21205.

Supported in part by NIH Research Grants Nos. EY01849 and EY00158.

Accepted for publication January 28, 1983




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