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Adrenoleuko-dystrophy (ALD)

Clinical and CT features of a childhood variant

Department of Neurology (Drs. Marler and O'Neill) and Radiology (Dr. Forbes), Mayo Clinic and Foundation, Rochester, MN, and the John F. Kennedy Institute and Department of Neurology (Dr. Moser), Johns Hopkins Medical Institutions, Baltimore, MD.

A variant of childhood adrenoleukodystrophy (ALD) affected two male cousins. The characteristic features include a progressive frontal lobe syndrome, frontal pole CT hypodensity, abnormal levels of plasma very-long-chain fatty acids, and a family history consistent with X-linked inheritance.

Address correspondence and reprint requests to Dr. Marler, Department of Neurology, Mayo Clinic and Foundation, Rochester, MN 55905.

Accepted for publication January 6, 1983.

This article has been cited by other articles:

				A. K. Afifi, A. H. Menezes, L. A. Reed, and W. E. Bell Atypical Presentation of X-Linked Childhood Adrenoleukodystrophy With an Unusual Magnetic Resonance Imaging Pattern J Child Neurol, November 1, 1996; 11(6): 497 - 499. [PDF]

				A. K. Percy Review Article: The Inherited Neurodegenerative Disorders of Childhood: Clinical Assessment J Child Neurol, April 1, 1987; 2(2): 82 - 97. [Abstract] [PDF]