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Department of Neurology and the Neurobehavior Program, UCLA School of Medicine, and the Neurobehavior Unit VAMC, West Los Angeles (Brentwood Division), Los Angeles, CA.
Twelve patients with the Klüver-Bucy syndrome (KBS) are described. The syndrome occurred in head trauma, Alzheimer's disease, Pick's disease, and following herpes encephalitis. KBS was transient after head trauma but was a persistent feature of the postencephalitic syndrome. In all cases KBS was combined with aphasia, amnesia, or dementia. Human KBS resembles the monkey syndrome, but in humans there is a more elaborate complex of behavioral disturbances. The behavioral manifestations are produced by bilateral temporal lobe dysfunction. Partial expression of the syndrome may have localizing validity.
Address correspondence and reprint requests to Dr. Benson, Reed Neurological Research Center, 710 Westwood Plaza, Los Angeles, CA 90024.
This research was supported by the Veterans Administration.
Presented in part at the thirty-fourth annual meeting of the American Academy of Neurology, Washington, DC, April 1982.
Accepted for publication January 6, 1983.
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