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Adrenoleukomyelo-neuropathy presenting as spinocerebellar degeneration

University Department of Neurology, Institute of Psychiatry and King's College Hospital Medical School, Denmark Hill, London, United Kingdom.

A spinocerebellar syndrome has been described rarely in adrenoleukodystrophy. We report a family containing three cases of typical adrenoleukodystrophy, and one patient with a slowly progressive spinocerebellar syndrome. A high index of suspicion and the ACTH stimulation test are required when dealing with multisystem neurologic disease of unknown origin.

Address correspondence and reprint requests to Dr. Marsden, University Department of Neurology, Institute of Psychiatry and King's College Hospital Medical School, Denmark Hill, London SE5, United Kingdom.

Dr. Obeso's work was suported by the British Medical Research Council and Dr. Lang's work was supported by the Canadian Medical Research Council.

Accepted for publication February 22, 1982.

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