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Treatment of action tremor in multiple sclerosis with isoniazid

Section of Neurology, Department of Medicine, Brigham and Women's Hospital, and the Department of Neurology. Harvard Medical School, Boston, MA.

Four patients with disabling action tremor in the setting of MS were treated with isoniazid (800 to 1200 mg per day). All patients showed significant improvement of the tremor, allowing more functional use of their extremities. To the best of our knowledge, this is the only medical treatment for this type of tremor.

Address correspondence and reprint requests to Dr. Hallett, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115.

Accepted for publication December 10, 1981.

This article has been cited by other articles:

				S. H. Alusi, J. Worthington, S. Glickman, and P. G. Bain A study of tremor in multiple sclerosis Brain, April 1, 2001; 124(4): 720 - 730. [Abstract] [Full Text] [PDF]

				S H ALUSI, S GLICKMAN, T Z AZIZ, and P G BAIN Tremor in multiple sclerosis J. Neurol. Neurosurg. Psychiatry, February 1, 1999; 66(2): 131 - 134. [Full Text]