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Opsoclonus in Hemophilus influenzae meningitis

Departments of Neurology (Drs. Rivner, Green, and Dyken), and Ophthalmology (Dr. Jay), Medical College of Georgia, and the Veterans Administration Medical Center, Augusta, GA.

we studied a 3-month-old boy who had opsoclonus in association with acute bacterial meningitis. The CSF IgG and IgM were elevated acutely, gradually returning to normal with clinical improvement. Correspondingly, CSF cytomorphology showed excessive plasmocytosis and a higher proportion of reactive lymphocytes than expected in an acute bacterial meningitis. These abnormalities in CSF cytology are effects of an abnormal immune response in the CNS, and provide evidence to support an immunopathic basis to opsoclonus.

Address correspondence and reprint requests to Dr. Rivner. Department of Neurology, Medical College of Georgia, Augusta. GA 30912.

Accepted for publication November 13, 1981

This article has been cited by other articles:

				S. L. Kaplan and M. A. Fishman Review Article: Update on Bacterial Meningitis J Child Neurol, April 1, 1988; 3(2): 82 - 93. [Abstract] [PDF]

				K. B. Digre Opsoclonus in Adults: Report of Three Cases and Review of the Literature Arch Neurol, November 1, 1986; 43(11): 1165 - 1175. [Abstract] [PDF]