HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Correspondence: Submit a response Alert me when this article is cited Alert me when Correspondence are posted Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Volpe, B. T. Articles by Gazzaniga, M. S. Search for Related Content PubMed PubMed Citation Articles by Volpe, B. T. Articles by Gazzaniga, M. S.

Cortical mechanisms involved in praxis

Observations following partial and complete section of the corpus callosum in man

Division of Cognitive Neuroscience (Drs. Volpe, Sidtis, Holtzman, and Gazzaniga) Cornell University, New York, NY, and the Department of Neurosurgery (Dr. Wilson), Dartmouth-Hitchcock Medical Center, Hanover. NH.

In patients who have undergone complete section of the corpus callosum for intractable epilepsy, lateralized presentation of visual nonverbal stimulation showed that the coordination of motor acts by either hand is controlled exclusively by the contralateral hemisphere. When two patients had serial operations consisting of an initial division of the splenium and posterior 3 cm, followed by complete callosal division, an opportunity arose to test the explicit cortical pathways involved in ipsilateral control. Between operations, these patients could not coordinate movements of the hand ipsilateral to the hemisphere receiving the command. This suggested that for visual nonverbal stimulation, the posterior 3 cm of corpus callosum is necessary for control of the ipsilateral hand; the rostra1 callosum cannot transfer sensorimotor commands. Also, contrary to current views, each hemisphere can carry out sequentially dependent motor activity.

Address correspondence and reprint requests to Dr. Volpe, Division of Cognitive Neuroscience, Cornell University Medical School, 1300 York Avenue, New York, NY 10021.

Aided by the USPHS Grant No. NS15053-3, and the Alfred P. Sloan, McKnight, and Burke Foundations Accepted for publication October 16,1981.

This article has been cited by other articles:

				L. Bonzano, A. Tacchino, L. Roccatagliata, G. Abbruzzese, G. L. Mancardi, and M. Bove Callosal Contributions to Simultaneous Bimanual Finger Movements J. Neurosci., March 19, 2008; 28(12): 3227 - 3233. [Abstract] [Full Text] [PDF]

				H. Lausberg, R. F. Cruz, S. Kita, E. Zaidel, and A. Ptito Pantomime to visual presentation of objects: left hand dyspraxia in patients with complete callosotomy Brain, February 1, 2003; 126(2): 343 - 360. [Abstract] [Full Text] [PDF]

				J. C. Eliassen, K. Baynes, and M. S. Gazzaniga Anterior and posterior callosal contributions to simultaneous bimanual movements of the hands and fingers Brain, December 1, 2000; 123(12): 2501 - 2511. [Abstract] [Full Text] [PDF]

				L. M. Parsons, J. D. E. Gabrieli, E. A. Phelps, and M. S. Gazzaniga Cerebrally Lateralized Mental Representations of Hand Shape and Movement J. Neurosci., August 15, 1998; 18(16): 6539 - 6548. [Abstract] [Full Text] [PDF]

				G. L. Risse, J. Gates, G. Lund, R. Maxwell, and A. Rubens Interhemispheric Transfer in Patients With Incomplete Section of the Corpus Callosum: Anatomic Verification With Magnetic Resonance Imaging Arch Neurol, April 1, 1989; 46(4): 437 - 443. [Abstract] [PDF]