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Division of Paediatric Neurology (Drs. Dunn and Verity), the Division of Neurosurgery (Dr. Moyes), the Division of Neurological Sciences (Dr. Wada), and the Department of Diagnostic Radiology (Dr. Lapointe), University of British Columbia, Vancouver, B.C., and the Department of Psychology (Dr. Strauss), University of Victoria, Victoria, B.C., Canada.
Eight patients were studied 3 to 16 years (mean, 10 years) after cerebral hemispherectomy. Seven had infantile hemiplegia, and one had Sturge-Weber disease. Preoperative assessment included EEG responses to intracarotid drug injections. Postoperative complications occurred in seven patients. The operation was followed by a marked reduction in seizure frequency and improvement in behavior, with little change in intellect or hemiplegia. Neuropsychological assessment performed in four patients showed that they were not aphasic, but nonverbal spatial abilities were poor. CT showed marked shift of the remaining hemisphere in five of six patients scanned.
Address correspondence and reprint requests to Dr. Verity, Bristol Royal Hospital for Sick Children, St. Michaels's Hill, Bristol. Avon, England.
Presented in part at the thirty-third annual meeting of the American Academy of Neurology, Toronto, Ontario, April 1981.
Accepted for publication October 19, 1981.
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