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Ischemic optic neuropathy

A complication of cardiopulmonary bypass surgery

Department of Neurology and Ophthalmology (Drs. Sweeney. Breuer. Furlan, Lederman, Hanson, and Tomsak), The Cleveland Clinic Foundation, Cleveland, OH, and the Department of Neurology (Drs. Waybright and Selhorst), Medical College of Virginia. Richmond. VA.

Ischemic optic neuropathy followed cardiopulmonary bypass surgery in the postoperative period in 7 of 7685 consecutive procedures. The visual loss was unilateral in four patients and bilateral in three and there was little improvement. This ischemic infarction of the optic nerve disk was attributed to hypotension, hypothermia, and activation of certain complement factors by the bypass procedure.

Address correspondence and reprint requests to Dr. Sweeney. Department of Neurology, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44106.

Accepted for publication September 30. 1981.

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