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Peripheral neuropathies and tremor

Service de Neurologie (Drs. Said and Cesaro). Centre Hospitalier de Bicetre. Université Paris Sud. and Laboratoire de Physiologie (Dr. Bathien), Faculté de Médecine Saint Antoine. Paris. France.

We studied 14 patients with tremor and acquired peripheral neuropathies of different origin. Minimal weakness was the only clinical finding common to all patients. Sensory changes, etiology, and course of the neuropathy varied. No unique pattern of peripheral nerve histopathology could be demonstrated. Slowing of conduction velocity of Ia fibers was found, but the role played by impairment of sensory inputs remains unclear. Tremor associated with peripheral neuropathy seems to be due to enhancement of physiologic tremor by minimal weakness.

Address correspondence and reprint requests to Dr. Said. Service de Neurologie. Centre Hospitaller de Bicetre, 94270 Le Kremlin Bicêtre. France.

Accepted for publication September 29, 1981.

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