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NEUROLOGY 1982;32:432
© 1982 American Academy of Neurology

Beneficial effects of lisuride in Meige disease

Federico Micheli, M.D., Manuel M. Fernández Pardal, M.D. and Ramón C. Leiguarda, M.D.

Institute de Investigaciones Neurológicas (Dr. R. Carrea) F.L.E.N.I., (Dr. Leiguarda) and the Cátedra de Neurologia—Hospital Escuela Gral. San Martin (Drs. Micheli and Pardal), Universidad de Buenos Aires, Argentina.

We studied the therapeutic effects of apomorphine, bromocriptine, and lisuride on the dystonic spasms of two patients with Meige disease. Lisuride, a potent dopamine receptor agonist, and apomorphine had equal efficacy in lessening facial dyskinesia, while bromocriptine had no consistent effect. Lisuride can be an excellent drug in the treatment of this disabling disorder.

Address correspondence and reprint requests to Dr. Leiguarda, Centro de Investigaciones Neurológicas (Dr. R. Carrea) F.L.E.N.I. Ayacucho 2166, (1112) Buenos Aires. Argentina.

Accepted for publication September 2, 1981.






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