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Neurology Service, Massachusetts General Hospital, Massachusetts Rehabilitation Hospital and the Department of Neurology, Harvard Medical School, Boston, MA.
We observed acute onset of delayed psychosis in 8 patients 1 month to 11 years after right temporoparietooccipital (TPO) stroke or trauma. The psychotic disorder included hallucinations and, in some patients, delusions and agitation. All patients had spatioconstructional difficulties. None had an earlier psychiatric disorder. Seven of eight patients had clinical seizures, often in close temporal relationship to the psychosis. The pathophysiology of the psychosis may be related to that of the epilepsy.
Address correspondence and reprint requests to Dr. Levine, Neurology Service, Massachusetts General Hospital. Fruit Street. Boston. MA 02114.
This research was supported in part by Grant No. NS-13102 from the National Institutes of Health and by a grant from the Rowland Foundation to Dr. Levine. Dr. Finklestein is a recipient of a clinician-scientist award from the American Heart Association.
Accepted for publication August 4, 1981.
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