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Progressive multifocal leukoencephalopathy

Failure of cytarabine therapy

Division of Neuropathology, Department of Pathology (Drs. Smith and Sima), Division of Infectious Diseases, Department of Medicine (Dr. Salit), Division of Neurosurgery. Department of Surgery (Dr. Gentili), Toronto General Hospital and University of Toronto, Toronto, Canada.

A 32-year-old man had biopsy-proven progressive multifocal leukoencephalopathy (PML) and long-standing sarcoidosis. Treatment with several courses of cytarabine failed, and the patient died of the neurologic disease. Reports of therapeutic experiences in PML are summarized.

Address correspondence and reprint requests to Dr. Sima. Division of Neuropathology, Department of Pathology, Banting Institute, 100 College Street, Toronto, Canada.

Accepted for publication August 4, 1981.

This article has been cited by other articles:

				L. W. Blum, R. A. Chambers, R. J. Schwartzman, and L. J. Streletz Progressive Multifocal Leukoencephalopathy in Acquired Immune Deficiency Syndrome Arch Neurol, February 1, 1985; 42(2): 137 - 139. [Abstract] [PDF]