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NEUROLOGY 1982;32:1317
© 1982 American Academy of Neurology

Phenytoin-induced arthritis

Ruth Stalnikowicz, M.D., Morris Mosseri, M.D. and Oded Shalev, M.D.

Department of Internal Medicine, Hadassah University Hospital-Mount Scopus, Jerusalem, Israel.

An 81-year-old woman developed acute arthritis as a complication of phenytoin treatment. Fever and eosinophilia accompanied the arthritis, which subsided on discontinuation of the drug and reappeared after its reintroduction. The mechanism responsible for this drug reaction may be immunologically mediated.

Address correspondence and reprint requests to Dr. Stalnikowicz, Department of Internal Medicine, Hadassah University Hospital-Mount Scopus, PO Box 24035, il-91240 Jerusalem, Israel.

Accepted for publication April 13, 1982.






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