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Demyelinating neuropathy accompanying Lyme disease

Departments of Neurology (Dr. Sterman) and Medicine (Drs. Nelson and Barclay), School of Medicine, SUNY at Stony Brook, Stony Brook, NY.

Lyme disease is characterized by skin, joint, heart, and central or peripheral neurologic disease. We studied a patient with typical Lyme disease, including a demyelinating neuropathy, who had many characteristics of the Guillain-Barré syndrome, although it was accompanied by CSF pleocytosis. Immunologic abnormalities occurring in Lyme disease suggest immune pathogenesis of the peripheral demyelination.

Address correspondence and reprint requests to Dr. Sterman, Department of Neurology, School of Medicine, SUNY at Stony Brook, Stony Brook, NY 11794.

Presented in part at the thirty-fourth annual meeting of the American Academy of Neurology, Washington, DC, April 1982.

Accepted for publication March 31, 1982.

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