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NEUROLOGY 1982;32:1285
© 1982 American Academy of Neurology

Vincristine-induced laryngeal nerve paralysis

Peyton Delaney, M.D.

Department of Medicine, Division of Neurology, University of Texas Health Science Center, San Antonio, TX.

The neurotoxicity of the Vinca alkaloids vincristine and vinblastine is well recognized. Less recognized is laryngeal nerve paralysis induced by these chemotherapeutic agents. This potentially dangerous paralysis is usually reversible when the drug is withdrawn, but other causes of hoarseness in a cancer patient must be considered. I add two cases to 19 previously documented.

Address correspondence and reprint requests to Dr. Delaney, Department of Medicine, Division of Neurology, University of Texas Health Science Center, San Antonio, TX 78284.

Accepted for publication April 21, 1982.






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