HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Correspondence: Submit a response Alert me when this article is cited Alert me when Correspondence are posted Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Galassi, G. Articles by Colombo, A. Search for Related Content PubMed PubMed Citation Articles by Galassi, G. Articles by Colombo, A.

Peripheral neuropathy in multiple system atrophy with autonomic failure

Department of Neurology, University of Modena (Drs. Galassi. Gibertoni, and Colombo), the Neurological Clinic, University of Milan (Dr. Nemni), and the Division of Nephrology, University of Modena (Dr. Baraldi). Modena, Italy.

Two patients with multiple system atrophy, autonomic failure, and peripheral neuropathy are reported. EMG and conduction study in both muscle and sural nerve histology in one patient documented the involvement of the neuromuscular system. Morphologic study of the biopsied nerve showed marked reduction of large myelinated fibers, whereas the unmyelinated axons were totally spared. The latter finding provides evidence that the sympathetic nervous system contributes few, if any, axons to the total population of unmyelinated fibers in the human sural nerve. Peripheral nerve damage may be common in the Shy-Drager syndrome.

Address correspondence and reprint requests to Dr. Galassi. Department of Neurology, University of Modena, Medical School, Via del Pozzo 71, 41100, Modena, Italy.

Accepted for publication March 30, 1982.