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Ipecac-induced myopathy simulating dermatomyositis

Departments of Neurology (Drs. Bennett, Spiro, Pollack and Zucker) and Pediatrics, Montefiore Hospital and Medical Center, and the Albert Einstein College of Medicine of Yeshiva University, Bronx, NY.

We studied a young woman with an eating disorder. To induce vomiting, she took syrup of ipecac daily for 2 years, and then developed insidious, progressive muscle weakness. Skin findings were similar to those of dermatomyositis. Muscle biopsy, however, was similar to experimental emetine myopathy and lacked inflammatory features. Upon cessation of ipecac abuse, strength returned. We believe that this patient had ipecac-induced muscle weakness.

Address correspondence and reprint requests to Dr. Bennett, Section of Pediatric Neurology, The Brook dale Hospital Medical Center, Brooklyn, NY 11212.

Accepted for publication June 17, 1981.

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