HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Correspondence: Submit a response Alert me when this article is cited Alert me when Correspondence are posted Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Saper, C. B. Articles by Jarowski, C. I. Search for Related Content PubMed PubMed Citation Articles by Saper, C. B. Articles by Jarowski, C. I.

Leukemic infiltration of the cerebellum in acute myelomonocytic leukemia

Departments of Neurology (Dr. Saper) and Medicine (Dr. Jarowski), Division of Hematology-Oncology, New York Hospital-Cornell Medical Center, New York, NY.

A 31-year-old woman with acute myelomonocytic leukemia presented with meningeal signs and a cerebellar mass attributed to leukemic infiltration. The mass disappeared with radiation therapy and intraventricular chemotherapy, but the patient subsequently suffered several spinal nerve root recurrences, disseminated herpes zoster, and progressive multifocal leukoencephalopathy. At autopsy, there was no trace of the meningeal leukemia or cerebellar infiltrate. This case illustrates several of the neurologic complications of acute nonlymphocytic leukemia, and raises the question whether patients with the myelomonocytic form of this disease might benefit from prophylactic central nervous system treatment.

Address correspondence and reprint requests to Dr. Saper, Department of Neurology, Washington University School of Medicine, 660 S. Euclid, St. Louis, MO 63110.

Accepted for publication July 2, 1981.