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NEUROLOGY 1982;32:7
© 1982 American Academy of Neurology

Interictal psychopathology in patients with ictal fear

A quantitative investigation

Bruce P. Hermann, Ph.D., Sureyya Dikmen, Ph.D., Mark S. Schwartz, Ph.D. and William E. Karnes, M.D.

Department of Neurology, University of Illinois at the Medical Center (Dr. Hermann), Chicago, the Departments of Rehabilitation Medicine and Neurological Surgery, University of Washington (Dr. Dikmen). Seattle, WA, and the Section of Psychology (Dr. Schwartz) and Department of Neurology (Dr. Karnes), Mayo Clinic and Mayo Foundation. Rochester, MN.

We assessed the hypothesis that psychopathology is overrepresented in patients with temporal lobe epilepsy (TLE) who experience ictal fear. Eleven such patients were matched with two control groups: patients who had TLE without ictal fear and patients who had generalized epilepsy. On several MMPI scales, the TLE-ictal fear group scored significantly higher than the two control groups, which did not differ ssignificantly from each other. Furthermore, the TLE-ictal fear group had more MMPI clinical scales that were pathologically elevated, had significantly more patients with histories of admission to psychiatric hospitals, and had more MMPI profiles that were psychotic than either of the control groups.

Address correspondence and reprint requests to Dr. Hermann, Department of Neurology, University of Illinois at the Medical Center, 912 South Wood Street, Chicago, IL 60612.

This study was supported in part by Grant No. 05-H-000150–11 from the DHHSPHS/MCH-FP, Region V (Dr. Hermann), and by Research Grant No. G00 800 3029 from the NIHR and NIH Contract No. l-NS-6–2341 (Dr. Dikmen).

Accepted for publication July 2, 1981.




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