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NEUROLOGY 1982;32:49
© 1982 American Academy of Neurology

A prospective study of lacunar infarction using computerized tomography

Geoffrey A. Donnan, M.D., F.R.A.C.P., Brian M. Tress, M.B., B.S., M.R.A.C.R., F.R.C.R. and Peter F. Bladin, M.D., B.Sc., F.R.A.C.P.

Departments of Neurology (Drs. Donnan and Bladin) and Medicine (Dr. Donnan), Austin Hospital, University of Melbourne, and the Department of Radiology (Dr. Tress), Royal Melbourne Hospital, University of Melbourne, Australia.

Sequential computed tomography (CT) scans were performed for up to 7 months on patients who presented with clinical evidence of lacunar infarction or ischemia. Sixty-nine percent of the patients showed lacunar infarction, and a negative scan did not suggest a better prognosis in stroke patients. Of patients with transient ischemic attacks (TIA) (lacunar), those with repeated bursts of hemiplegia (capsular warning syndrome) were more likely to be CT-positive (p < 0.01). The clinical features of patients with lacunar infarction were examined and correlated with the features of infarction. Partial syndromes were found in 32% of the cases and included examples of monoparesis and dysarthria alone.

Address correspondence and reprint requests to Dr. Donnan, Department of Neurlogy, Austin Hospital, Heidleberg 3084, Victoria, Australia.

Accepted for publication June 18, 1981.




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