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NEUROLOGY 1982;32:18
© 1982 American Academy of Neurology

Pseudoseizures

Diagnostic evaluation

Don W. King, M.D., Brian B. Gallagher, M.D., Ph.D., Alice J. Murvin, R.N., Dennis B. Smith, M.D., Donald J. Marcus, M.D., Lawrence C. Hartlage, Ph.D. and L. Charles Ward, III, Ph.D.

Departments of Neurology (Drs. King. Gallagher. Smith. Marcus. Hartlage. and Ms. Murvin) and Psychiatry, (Dr. Ward) Medical College of Georgia. Augusta, GA.

A prospective study of pseudoseizures using prolonged video-electroencephalographic (EEG) recording was carried out in 60 patients. Of 33 patients with episodes of uncertain mechanism, a diagnosis based on recorded episodes was made in 18 (55%). Twelve (36%) had pseudoseizures; 6 (18%) had epileptic seizures. Ten additional patients had epileptiform EEGs compatible with epilepsy. Of 27 patients with presumably uncontrolled epileptic seizures, 4 (15%) had recorded pseudoseizures. Prediction of the nature of the episode by the admitting neurologist was accurate in 67% of cases. Determination from observations of unit personnel and neurologists was correct in less than 80% of episodes.

These data suggest that pseudoseizures occur frequently in patients being evaluated for epilepsy or suspected epilepsy. The clinical differentiation between epileptic seizures and pseudoseizures is often inaccurate. This differentiation is facilitated by prolonged video-EEG recording.

Address correspondence and reprint requests to Dr. King, Department of Neurology, Medical College of Georgia, Augusta, GA 30912.

This work was supported in part by Research Contract, No. l-NS-6–2340, from the National Institutes of Health, Public Health Service.

Presented at the thirty-third annual meeting of the American Academy of Neurology, Toronto, Canada, April 1981.

Accepted for publication June 18, 1981.




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