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Optic neuritis in familial MS

Department of Clinical Neurological Sciences, Division of Neurology, University Hospital, London, Ontario, Canada.

Seven patients with optic neuritis were found in a study of 84 families with familial multiple sclerosis (MS). Evidence obtained from neurologic examination and electrophysiologic testing tended to confirm monosymptomatic optic nerve involvement. The presence of isolated optic neuritis in these families implies that MS and at least some cases of isolated optic neuritis have a similar etiology.

Address correspondence and reprint requests to Dr. Ebers, Department of Clinical Neurological Sciences, Division of Neurology, University Hospital, 339 Windermere Road, P.O. Box 5339, Postal Station A, London, Ontario N6A 5A5, Canada.

This research was supported by grants from the P.S.I. Foundation and Medical Research Council of Canada.

Accepted for publication December 30, 1980.

This article has been cited by other articles:

				G. C. Ebers Optic Neuritis and Multiple Sclerosis Arch Neurol, July 1, 1985; 42(7): 702 - 704. [Abstract] [PDF]