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Exchange transfusion in neonatal myasthenia gravis

Departments of Neurology (Drs. Donat) and Pediatrics (Dr. J. F. G. Donat), Louisiana State University Medical Center, Shreveport, LA, and the Neuroimmunology Laboratory, Departments of Neurology and Immunology (Dr. Lennon), Mayo Clinic, Rochester, MN.

An infant with transient neonatal myasthenia gravis had a double-blood-volume exchange transfusion because of maternal-fetal blood group incompatibility. This seemed to accelerate both decline in antiacetylcholine antibody titer and clinical improvement.

Address correspondence and reprint requests to Dr. J. F. G. Donat, Assistant Professor of Neurology and Pediatrics, University of Saskatchewan, Saskatoon, Saskatchewan, Canada S7N 0x0.

Accepted for publication September 25, 1980

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