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Polyneuropathy after massive exposure to parathion

Department of Neurology (Drs. de Jager and van Weerden), the Respiratory Intense Care Unit (Drs. de Jager and de Monchy), and the Department of Pathology (Dr. Houthoff7, Academisch Ziekenhuis, Groningen, The Netherlands.

Many organophosphorus compounds, including the organophosphate insecticides, may cause polyneuropathy of delayed onset. An exception is parathion, which has been considered the prototype of nonneurotoxic cholinesterase inhibitors. Nevertheless, we describe a patient with delayed polyneuropathy after suicidal ingestion of parathion.

Address correspondence and reprint requests to Dr. de Jager, Department 01 Neurology, Academisch Ziekenhuis, Groningen, The Netherlands.

Accepted for publication August 5, 1980.

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