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NEUROLOGY 1981;31:442
© 1981 American Academy of Neurology

Progressive supranuclear palsy, computed tomography, and response to Antiparkinsonian drugs

S. Haldeman, Ph.D., M.D., J. W. Goldman, M.D., J. Hyde, M.D. and H.F.W. Pribram, M.D., F.R.C.P.(C)

Department of Neurology (Drs. Haldeman, Goldman, and Hyde) and Radiology (Dr. Pribram), University of California, Irvine, and Veterans Administration Hospital, Long Beach, CA.

Three patients with progressive supranuclear palsy demonstrated atrophy of the midbrain, pons, cerebellum, and cerebral hemispheres by computed tomography with horizontal, sagittal, and coronal reconstruction. Benztropine therapy resulted in improvement of speech and gait without significantly affecting the vertical gaze palsy.

Address correspondence and reprint requests to Dr. Haldeman, Department of Neurology, University of California Irvine Medical Center, 101 City Drive South, Orange, CA 92668.

Accepted for publication July 1, 1980.




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