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Increased incidence and prevalence of multiple sclerosis in Los Alamos County, New Mexico

Field Services Division Epidemiology Program Office (Dr. Hoffman), and the Center for Environmental Health (Dr. Zack), Centers for Disease Control, Atlanta, GA, the Department of Neurology, the University of New Mexico School of Medicine, and the Albuquerque Veterans Medical Center, Albuquerque, NM (Dr. Davis), and the University of Michigan School of Public Health, Ann Arbor, MI (Mr. Burch-fiel).

Address correspondence and reprint requests to Dr. Hoffman, Field Services Division, Epidemiology Program Office, Centers for Disease Control, Atlanta, GA 30333.

The incidence and prevalence of multiple sclerosis (MS) in Los Alamos County, New Mexico, were investigated because the number of reported cases appeared to have increased. The point prevalence on November 1, 1979, was 75.7 per 100,000, and average annual incidence rates for the periods 1960–1969 and 1970–1979 were 3.4 and 3.7 per 100,000, respectively. The rates of MS in Los Alamos County were greater than expected from previous epidemiologic surveys of North America. The unusual ethnic composition and high socioeconomic level of the population probably contributed to the increases.