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The effect of symptom duration on cognitive and motor perfomname in parkinsonism

Department of Neurolom, Neuropsychology Laboratory, University of Wisconsin Center for Health Sciences, Madison, Wisconsin.

europsychologic test performance was examined in a normal control group and in three groups of Parkinson disease patients, with symptoms for 2 years or less, for 3 to 5 years, or for 6 to 15 years. On a test battery sampling a wide variety of cognitive and motor abilities, significant intergroup differences occurred primarily on tasks with a primary motor component, although mild intergroup cognitive impairment was also demonstrated. The results suggested that maximal deterioration occured during the first 5 years of symptoms, with few significant additional changes after that.

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