| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Department of Neurology, Boston University School of Medicine and Boston Veterans' Administration Medical Center, Boston, Massachusetts (Drs. Feldman, Niles, and Sax, and Ms. Kelly-Hayes); the Department of Biomathematics, University of California, Los Angeles, California, (Dr. Dixon); the Department ofBiostatistics, University of Washington, School ofPubiicHealth, Seattle, Washington (Dr. Thompson); and the American Public Health Association, Washington, D.C. tDr. Landau).
We conducted a double-blind controlled study of individuals exposed to arsenic trioxide in a copper-smelting factory. Subjects fell into three categories of peripheral neuropathy: none, subclinical, and clinical. The subclinical group had no symptoms or signs of numbness or reduced reflexes, but did have reduced nerve conduction velocity and amplitude measurements. Clinical neuropathy groups had signs and symptoms of neuropathy and electrophysiologic abnormalities. The clinical and subclinical groups correlated with increased content of arsenic in urine, hair, and nails. The incidence of subclinical and clinical neuropathy was greater in arsenic workers than in unexposed controls.
This article has been cited by other articles:
|
|
 |
|
  J R. Pilsner, X. Liu, H. Ahsan, V. Ilievski, V. Slavkovich, D. Levy, P. Factor-Litvak, J. H Graziano, and M. V Gamble Genomic methylation of peripheral blood leukocyte DNA: influences of arsenic and folate in Bangladeshi adults Am. J. Clinical Nutrition, October 1, 2007; 86(4): 1179 - 1186. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. V Gamble, X. Liu, V. Slavkovich, J R. Pilsner, V. Ilievski, P. Factor-Litvak, D. Levy, S. Alam, M. Islam, F. Parvez, et al. Folic acid supplementation lowers blood arsenic Am. J. Clinical Nutrition, October 1, 2007; 86(4): 1202 - 1209. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Chou, J. Colman, C. Tylenda, and C. De Rosa Chemical-specific health consultation for chromated copper arsenate chemical mixture: port of Djibouti Toxicology and Industrial Health, May 1, 2007; 23(4): 183 - 208. [Abstract] [PDF]
|
|
|
|
 |
|
 D Otto, Y Xia, Y Li, K Wu, L He, J Telech, H Hundell, J Prah, J Mumford, and T Wade Neurosensory effects of chronic human exposure to arsenic associated with body burden and environmental measures Human and Experimental Toxicology, March 1, 2007; 26(3): 169 - 177. [Abstract] [PDF]
|
|
|
|
|
|
M. V Gamble, X. Liu, H. Ahsan, J R. Pilsner, V. Ilievski, V. Slavkovich, F. Parvez, Y. Chen, D. Levy, P. Factor-Litvak, et al. Folate and arsenic metabolism: a double-blind, placebo-controlled folic acid-supplementation trial in Bangladesh. Am. J. Clinical Nutrition, November 1, 2006; 84(5): 1093 - 1101. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. L. Kile, E. A. Houseman, E. Rodrigues, T. J. Smith, Q. Quamruzzaman, M. Rahman, G. Mahiuddin, L. Su, and D. C. Christiani Toenail Arsenic Concentrations, GSTT1 Gene Polymorphisms, and Arsenic Exposure from Drinking Water Cancer Epidemiol. Biomarkers Prev., October 1, 2005; 14(10): 2419 - 2426. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B D Beck, T M Slayton, C H Farr, D W Sved, E A Crecelius, and J F Holson Systemic uptake of inhaled arsenic in rabbits Human and Experimental Toxicology, April 1, 2002; 21(4): 205 - 215. [Abstract] [PDF]
|
|
|
|
 |
|
 O Rubens, I Logina, I Kravale, M Eglite, and M Donaghy Peripheral neuropathy in chronic occupational inorganic lead exposure: a clinical and electrophysiological study J. Neurol. Neurosurg. Psychiatry, August 1, 2001; 71(2): 200 - 204. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
