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NEUROLOGY 1978;28:842
© 1978 American Academy of Neurology

Deformed erythrocytes in muscular dystrophies

E. Grassi, B. Lucci, C. Marchini, S. Ottonello, M. Parma, R. Reggiani, G. L. Rossi and J. Tagliavini

Clinica Neurologica Universita di Parma (Drs. Grassi, Marchini, and Parma); the Divisione Neurologica A.S.M.N. di Reggio Emilia (Drs. Lucci and Reggiani); the Istituto di Biologia Molecolare Università di Parma (Drs. Ottonello and Rossi); and the Istituto di Genetica Università di Parma (Dr. Tagliavini), Parma Italy.

Because of previous reports of a possible correlation between echinocytogenesis and muscular dystrophies, we investigated the time-dependent development of echinocytes in the blood of normal subjects, patients, and healthy carriers of Duchenne dystrophy. There was a quantitatively significant increase of echinocytes in patients and carriers.

Dr. Grassi's address is Clmica Neurologica, Universita di Parma, Via del Quartiere 4,43300 Parma, Italy.

Accepted for publication January 4, 1978.






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