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Division of the corpus callosum for uncontrollable epilepsy

Sections of Neurosurgery and Neurology, Dartmouth-Hitchcock Medical Center, Hanover, New Hampshire, and the Department of Psychology and Social Science in Medicine, State University of New York at Stony Brook, New York.

Cerebral commissurotomy, the "split-brain" procedure, has been employed for the control of intractable seizures, in conjunction with moderate doses of anticonvulsant drugs. The results have been encouraging in several small series. The use of microsurgical techniques and the restriction of surgery to one commissure, the corpus callosum, has reduced morbidity without apparent change in result. The eight patients in our first series who underwent the prescribed division of several forebrain commissures are compared to the four patients in our second series who underwent division of the corpus callosum alone. The technique of callosotomy is described.

Dr. Wilson's address is Hitchcock Clinic, Hanover NH 03755.

Accepted for publication December 14, 1977.

This article has been cited by other articles:

				R. C. Green, J. R. Adler, and G. Erba Review Article: Epilepsy Surgery in Children J Child Neurol, July 1, 1988; 3(3): 155 - 166. [Abstract] [PDF]

				J. Sidtis, B. Volpe, J. Holtzman, D. Wilson, and M. Gazzaniga Cognitive interaction after staged callosal section: evidence for transfer of semantic activation Science, April 17, 1981; 212(4492): 344 - 346. [Abstract] [PDF]