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Strokes and ulcerative colitis

Department of Neurology, Neurological Institute of New York, Presbyterian Hospital, and Columbia University College of Physicians and Surgeons, New York City.

One adolescent and two young adults had ulcerative colitis and cerebral thrombosis. All survived with neurologic deficit. These patients had no other predisposing factor for cerebrovascular disease. Systemic arterial and venous thromboembolic complications occur often in ulcerative colitis, but stroke is uncommon. Abnormalities in the early stages of clotting may be responsible, and the risk of thromboembolic phenomena in young patients seems to increase with exacerbations of this form of chronic inflammatory bowel disease, and possibly with regional enteritis as well.

Dr. Fahn's address is 710 West 168th Street, New York, NY 10032.

Accepted for publication May 6, 1977.

This article has been cited by other articles:

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				M. S. Scher Maternal Ulcerative Colitis and Fetal Brain Injury: Long-Term Neurologic Outcome J Child Neurol, November 1, 2007; 22(11): 1293 - 1296. [Abstract] [PDF]

				J. D. Pandian, R. D. Henderson, J. D. O'Sullivan, and T. Rajah Cerebral vasculitis in ulcerative colitis. Arch Neurol, May 1, 2006; 63(5): 780 - 780. [Full Text] [PDF]