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NEUROLOGY 1978;28:545
© 1978 American Academy of Neurology

Lesion localization in aphasia with cranial computed tomography and the Boston Diagnostic Aphasia Exam

MARGARET A. NAESER, Ph.D. and ROBERT W. HAYWARD, M.D.

Departments of Audiology and Speech Pathology, and Radiology, Veterans Administration Hospital and Stanford University Medical Center, Palo Alto. California.

Nineteen stable left-hemisphere stroke patients with aphasia were evaluated by the Boston Diagnostic Aphasia Examination (BDAE) and the Token Test (TT), and by cranial computed tomography (CT). The types of aphasia included Broca (three patients), Wernicke (four patients), conduction (four patients), transcortical motor (four patients), and global (four patients). The lesions, as localized by CT scan, were superimposed onto five composite lesion localization maps for these five aphasia syndromes. There was good correlation between BDAE aphasia type and lesion localization. On CT scans, the locations of cortical language areas lie in a specific relationship to parts of the ventricular system.

Dr. Naeser's address is Aphasia Research Unit, Veterans Administration Hospital (116-B), 150 South Huntington Avenue, Boston, MA 02130.

This study was supported by the Medical Research Service, Veterans Administration.

This paper was presented in part at the Academy of Aphasia Meetings, Miami, Florida, October, 1976.

Accepted for publication May 20, 1977.




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