HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Correspondence: Submit a response Alert me when this article is cited Alert me when Correspondence are posted Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by PORTER, R. J. Articles by LACY, J. R. Search for Related Content PubMed PubMed Citation Articles by PORTER, R. J. Articles by LACY, J. R.

Diagnostic and therapeutic reevaluation of patients with intractable epilepsy

Epilepsy Branch, Neurological Disorders Program, National Instituteof Neurological and Communicative Disorders and Stroke, National Institutes of Health, Bethesda, Maryland.

Intensive monitoring techniques were used to improve seizure diagnosis and control in 23 patients with intractable epilepsy: (1) Video recording of clinical seizures and the ictal EEG, (2) long-term telemetered EEG recordings, and (3) frequent determination of plasma antiepileptic drug concentrations. Patients were monitored in the hospital for an average of 8 weeks and after discharge were followed for an average of 8 months. At follow-up, 70 percent of the patients continued to have improved seizure control as compared with baseline studies, 83 percent had decreased toxicity, and about half had made gains in social adjustment. Use of the techniques described can make a significant contribution to patients previously considered intractable to therapy.

Reprint requests should be addressed to Dr. Porter, Epilepsy Branch, Federal Building, Room 114, NINCDS, Bethesda, MD 20014.

Presented in part at the twenty-eighth annual meeting of the American Academy of Neurology, April 26-May 1, 1976, Toronto, Canada.

Accepted for publication April 1977.

This article has been cited by other articles:

				M. J. Brodie and M. A. Dichter Antiepileptic Drugs N. Engl. J. Med., January 18, 1996; 334(3): 168 - 175. [Full Text] [PDF]