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Methyl bromide intoxication

Neurologic features, including simulation of Reye syndrome

Departments of Neurology and Pathology (Neuropathology), Univenity of Kentucky College of Medicine, Lexington, Kentucky.

Three family members intoxicated with methyl bromide presented with a variety of neuropsychiatric manifestations including coma, severe status epilepticus, hyporeflexia, and acute psychosis. The simulation of Reye syndrome in the child emphasizes the need for careful toxicologic screening of all children presenting with this syndrome. The initial diagnostic difficulty encountered in these cases emphasizes the need for heightened awareness of the toxic chemicals used in local industries and the clinical manifestations of their intoxication.

Dr. Shields address is Department of Neurology, University of Kentucky College of Medicine, Lexington, KY 40506.

Accepted for publication December 27, 1976.

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